Doctors prescribe natamycin eye drops for: Fungal keratitis (a serious corneal infection, often from plant material or contact lens contamination) Other fungal infections of the eye surface or conjunctiva Sometimes as a preventive measure after certain eye surgeries if fungal risk is high It’s not for bacterial or viral eye infections. If your eye is red and watery but not producing thick discharge, it might not be a fungus and this medication won’t help.

Natamet 5% 3 ml

Natamet 5% 3 ml (Natamycin) is a prescription antifungal eye drop that contains natamycin 5%, used to treat fungal infections of the eye such as fungal keratitis (corneal infection) and other ocular fungal infections. It works by binding to the fungal cell membrane and killing the fungus. It’s typically applied frequently throughout the day, and treatment can last several weeks. Temporary irritation and blurred vision are common, and it’s important to avoid contact lenses during treatment and finish the full course even if symptoms improve.

Natamet 5% 3 ml

Variant	Price	Units
3 Eye Drop	$13.90	$4.63
6 Eye Drop	$24.60	$4.10
9 Eye Drop	$38.10	$4.23

Category: Eye care

Tags: antifungal eye medication, corneal infection treatment, eye fungus infection, fungal keratitis treatment, Natamet 5% 3 ml, natamycin eye drops, ocular antifungal, ophthalmic suspension, pink eye fungus care, prescription eye drops

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Medically Reviewed By

Dr. Emily Carter

Senior Clinical Pharmacist

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📋 Product Description

Natamet 5% 3 ml (Natamycin) is one of those medications you don’t hear about until you really need it. If you’ve been diagnosed with a fungal eye infection, chances are your doctor wrote this prescription and you’re trying to figure out what you’re putting in your eye. People usually search for things like “natamycin eye drops,” “fungal keratitis treatment,” “eye fungus medication,” “natamycin 5% drops,” or “how to treat eye fungus.” Most Natamet products are natamycin 5% ophthalmic suspension. Since brand names can vary, please double-check your bottle to confirm the active ingredient and concentration. Natamycin is a polyene antifungal, which means it works by binding to the fungal cell membrane and creating holes that kill the fungus. It’s effective against many types of fungi that infect the cornea and other eye structures.

What it’s used for

Doctors prescribe natamycin eye drops for:

Fungal keratitis (a serious corneal infection, often from plant material or contact lens contamination)
Other fungal infections of the eye surface or conjunctiva
Sometimes as a preventive measure after certain eye surgeries if fungal risk is high

It’s not for bacterial or viral eye infections. If your eye is red and watery but not producing thick discharge, it might not be a fungus and this medication won’t help.

How to use it correctly

Eye drops sound simple, but technique matters for effectiveness:

Wash your hands first
Tilt your head back and pull down your lower eyelid
Hold the dropper close to your eye (but don’t touch it)
Instill the prescribed number of drops into the pocket
Close your eyes gently for a minute
Press a finger against the inner corner of your eye to prevent drainage

The dosing schedule is intense—usually every 1–2 hours at first, then tapering as the infection improves. This can last several weeks. Set phone reminders if you need to. Missing doses can let the fungus regrow.

What to expect during treatment

Fungal eye infections are stubborn. You might not see improvement for several days, and the redness and discharge can actually look worse at first as the fungus dies off. That’s normal. The key is to stick with the schedule and trust the process. Your vision will likely be blurry after each dose. That’s temporary. Don’t drive or do detail work until your vision clears.

Side effects that are common

Most people tolerate natamycin well, but you might notice:

Mild burning or stinging when the drops go in
Temporary blurred vision
Feeling like something is in your eye
Redness or irritation around the eyelids

If you get severe pain, swelling, hives, or vision changes that don’t clear up, call your doctor. You could be having an allergic reaction or the infection might be getting worse.

Precautions and what to avoid

Don’t wear contact lenses during treatment and for at least 24 hours after finishing. Contacts can reinfect your eye and trap fungus.
Don’t share your drops with anyone else
Don’t touch the bottle tip to your eye, lashes, or skin—contamination is a real risk
Avoid eye makeup until the infection is completely cleared

If you’re pregnant or breastfeeding, natamycin is generally considered safe, but let your doctor know anyway.

Storage and handling

Store the bottle at room temperature. Don’t freeze it. Shake well before each use (it’s a suspension, not a clear solution). If the liquid looks clumpy or discolored, don’t use it.

When to call your doctor

Get in touch if:

You’re not seeing any improvement after a week
Symptoms get worse (more pain, more discharge, vision getting blurrier)
You develop signs of an allergic reaction
You accidentally stop using it and don’t know how to restart

Fungal keratitis can lead to corneal scarring and vision loss if not treated aggressively, so this isn’t something to take lightly.

Available Strengths (as available in the market)

Natamycin ophthalmic products are most commonly available as:

5% suspension (3 mL, 5 mL, 10 mL bottles) – this product
5% ointment (less common, but available in some markets)

There aren’t many alternative strengths because 5% is the standard therapeutic concentration. If you see a different percentage, verify it with your pharmacist.

FAQs

1) What is Natamet 5% 3 ml (Natamycin) used for?

It’s an antifungal eye drop used to treat fungal infections of the eye, especially fungal keratitis (corneal infection). It won’t work for bacterial or viral eye infections.

2) How often should I use Natamet drops?

Usually every 1–2 hours at first, then your doctor will taper the frequency as the infection improves. Treatment often lasts several weeks.

3) Can I wear contact lenses while using Natamet?

No. Remove contacts before applying and don’t reuse them until the infection is completely gone and your doctor clears you.

4) What should I do if my eye isn’t getting better?

If there’s no improvement after a week, or symptoms worsen, call your doctor. You may need a different antifungal or the infection might not be fungal.

5) Is Natamycin safe during pregnancy?

Generally considered safe, but you should still tell your doctor if you’re pregnant or breastfeeding so they can confirm it’s appropriate for your situation.

size	3 Eye Drop, 6 Eye Drop, 9 Eye Drop

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Natamet 5% 3 ml

Natamet 5% 3 ml

What it’s used for

How to use it correctly

What to expect during treatment

Side effects that are common

Precautions and what to avoid

Storage and handling

When to call your doctor

Available Strengths (as available in the market)

FAQs

1) What is Natamet 5% 3 ml (Natamycin) used for?

2) How often should I use Natamet drops?

3) Can I wear contact lenses while using Natamet?

4) What should I do if my eye isn’t getting better?

5) Is Natamycin safe during pregnancy?

Reviews

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